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Mitsuo Shimada Selected Research

Histone Deacetylase 1

6/2019The Significance of MicroRNA-449a and Its Potential Target HDAC1 in Patients With Colorectal Cancer.
4/2015The relationship of CD133, histone deacetylase 1 and thrombospondin-1 in gastric cancer.
8/2011Expression of histone deacetylase 1 and metastasis-associated protein 1 as prognostic factors in colon cancer.
4/2008Expression of hypoxia-inducible factor-1alpha, histone deacetylase 1, and metastasis-associated protein 1 in pancreatic carcinoma: correlation with poor prognosis with possible regulation.
1/2007Clinical significance of histone deacetylase 1 expression in patients with hepatocellular carcinoma.

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Mitsuo Shimada Research Topics

Disease

155Neoplasms (Cancer)
07/2022 - 01/2002
67Hepatocellular Carcinoma (Hepatoma)
06/2022 - 01/2002
40Neoplasm Metastasis (Metastasis)
06/2022 - 01/2002
37Stomach Neoplasms (Stomach Cancer)
09/2022 - 03/2006
27Cholangiocarcinoma
07/2022 - 01/2002
24Colorectal Neoplasms (Colorectal Cancer)
07/2022 - 06/2007
21Rectal Neoplasms (Rectal Cancer)
09/2022 - 01/2005
19Pancreatic Neoplasms (Pancreatic Cancer)
07/2022 - 11/2004
16Carcinoma (Carcinomatosis)
11/2017 - 01/2002
15Carcinogenesis
01/2021 - 02/2002
13Colonic Neoplasms (Colon Cancer)
06/2021 - 01/2002
11Lymphatic Metastasis
03/2021 - 11/2002
11Liver Diseases (Liver Disease)
10/2018 - 01/2002
10Fibrosis (Cirrhosis)
12/2020 - 07/2002
9Ischemia
05/2018 - 11/2002
9Acute Liver Failure (Fulminant Hepatic Failure)
01/2009 - 01/2002
8Liver Neoplasms (Liver Cancer)
07/2022 - 02/2003
8Body Weight (Weight, Body)
09/2021 - 09/2008
8Hypoxia (Hypoxemia)
01/2017 - 04/2008
8Hemorrhage
04/2014 - 02/2003
7Adenocarcinoma
04/2022 - 04/2005
7Pancreaticobiliary Maljunction
02/2022 - 07/2012
7Hepatitis C
11/2017 - 02/2005
7Liver Cirrhosis (Hepatic Cirrhosis)
03/2016 - 01/2002
6Ileus
04/2022 - 07/2008
6Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2022 - 09/2007
6Infections
11/2017 - 01/2004
6Wounds and Injuries (Trauma)
09/2017 - 04/2009
6Reperfusion Injury
07/2017 - 09/2003
6Ascites
04/2017 - 08/2005
6End Stage Liver Disease
01/2008 - 01/2002
5Fatty Liver
01/2017 - 02/2004
5Weight Loss (Weight Reduction)
08/2015 - 05/2012
5Gallbladder Neoplasms (Gallbladder Cancer)
05/2014 - 03/2009
4Frailty
09/2022 - 01/2021
4Inguinal Hernia (Direct Inguinal Hernia)
01/2022 - 01/2012
4Inflammation (Inflammations)
03/2020 - 09/2014
4Diarrhea
01/2020 - 01/2012
4Liver Failure
01/2019 - 01/2003
4Hepatitis B
11/2008 - 08/2004

Drug/Important Bio-Agent (IBA)

26Proteins (Proteins, Gene)FDA Link
12/2021 - 02/2002
23Messenger RNA (mRNA)IBA
04/2022 - 02/2002
14Indicators and Reagents (Reagents)IBA
12/2021 - 02/2004
12MicroRNAs (MicroRNA)IBA
01/2022 - 01/2013
11Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2013
10Biological ProductsIBA
12/2021 - 05/2003
9Bevacizumab (Avastin)FDA Link
01/2022 - 04/2014
8Hepatitis B Surface Antigens (HBsAg)FDA Link
03/2015 - 07/2002
7AlbuminsIBA
03/2022 - 09/2008
7phytobacteriomycin (PBM)IBA
02/2022 - 07/2012
7Oxaliplatin (Eloxatin)FDA LinkGeneric
05/2021 - 08/2011
7Interleukin-6 (Interleukin 6)IBA
12/2020 - 04/2011
7BilirubinIBA
10/2020 - 08/2005
7Histone Deacetylases (Histone Deacetylase)IBA
01/2020 - 04/2008
7Fluorouracil (Carac)FDA LinkGeneric
11/2017 - 01/2005
7Peptides (Polypeptides)IBA
01/2017 - 07/2004
6CytokinesIBA
04/2022 - 08/2004
6Conditioned Culture MediaIBA
04/2022 - 08/2018
6Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2022 - 02/2010
6C-Reactive ProteinIBA
12/2021 - 03/2010
6Blood Glucose (Blood Sugar)IBA
09/2020 - 01/2011
6Histone Deacetylase InhibitorsIBA
01/2020 - 02/2003
6Cisplatin (Platino)FDA LinkGeneric
11/2017 - 09/2003
6GemcitabineFDA Link
11/2017 - 11/2004
6InterferonsIBA
01/2017 - 12/2008
512,13- dihydro- N- methyl- 6,11,13- trioxo- 5H- benzo(4,5)cyclohepta(1,2- b)naphthalen- 5,12- imineIBA
12/2020 - 01/2015
5Insulin (Novolin)FDA Link
10/2020 - 09/2014
5Histone Deacetylase 1IBA
06/2019 - 01/2007
5LigandsIBA
06/2018 - 01/2002
5EnzymesIBA
01/2014 - 04/2005
5Thymidylate SynthaseIBA
06/2012 - 03/2009
5Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA
06/2012 - 04/2007
4Anti-Bacterial Agents (Antibiotics)IBA
10/2021 - 12/2002
4Serum AlbuminIBA
03/2021 - 02/2004
4Sorafenib (BAY 43-9006)FDA Link
01/2021 - 04/2013
4Calcibiotic Root Canal SealerIBA
09/2020 - 10/2015
4Cadherins (E-Cadherin)IBA
02/2020 - 07/2003
4Valproic Acid (Depakote)FDA LinkGeneric
01/2020 - 12/2011
4Transcription Factors (Transcription Factor)IBA
01/2018 - 04/2008
4CreatinineIBA
08/2015 - 12/2002
4Thymidine PhosphorylaseIBA
05/2012 - 01/2002
4Antineoplastic Agents (Antineoplastics)IBA
01/2012 - 12/2003

Therapy/Procedure

46Liver Transplantation
12/2020 - 01/2002
44Hepatectomy
06/2022 - 01/2002
38Therapeutics
02/2022 - 11/2002
29Gastrectomy
09/2022 - 03/2006
25Drug Therapy (Chemotherapy)
06/2022 - 09/2003
11Chemoradiotherapy
05/2021 - 03/2011
10Splenectomy
03/2016 - 04/2002
8Lymph Node Excision (Lymph Node Dissection)
01/2016 - 01/2005
7Transplantation
12/2020 - 03/2002
7Radiotherapy
03/2020 - 07/2008
5Kampo Medicine (Kampo)
01/2016 - 07/2008
4Operative Surgical Procedures
05/2022 - 01/2009
4Adjuvant Chemotherapy
04/2022 - 05/2005
4Pancreaticoduodenectomy
02/2022 - 04/2007
4Radiofrequency Ablation
01/2017 - 07/2009
4Colectomy
01/2015 - 06/2009
4Laparotomy
08/2014 - 01/2009
4Artificial Liver (Bioartificial Liver)
09/2007 - 01/2003